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I have a strong intuitive fear that agencies are a danger to democratic use and governance of nanotechnology. They are not open. They are not properly accountable to constitutional checks and balances. They are corruptible to the extreme in that one man, the President of the US has great power over the appointments. Judge, jury, executioner and rule maker over who can design, make and use nanotechnology will be a PROFOUND power. Our Constitution was written to divide up power. Agencies were created for convenience with little worry as they had little enough power to be concerned about at the time of their creation. This is no longer the case. As our Founders felt it necessary to divide up power into three different branches with what minimal power man had over man in that century, should not the beyond epic power of nanotechnology be divided up with checks and balances?
Given time, Nanotechnology will allow power well beyond the power of misuse of force and taxation. Nanotechnology will shape life, be all seeing, all knowing, all creating and all controlling. It will be a power beyond historical reckoning. Power over nanotechnology must be divided up into Legislative, Judicial and Executive branches. These Branches must be accountable to the People. The only reason they must answer the People is that the People have Nanotechnology and the power to enforce their will.
To withstand Nanotechnology I believe our Government needs to be reformatted to comply with the Constitution literally. There are provisions for changing the Constitution if that does not suit our current and future needs. Reinterpretations not blatantly obvious by the literal writing of the Constitution need to be phased out and the Constitution modified by Constitutional process if need be.